SIRPB1 antibody (AA 72-309)

Catalog No. ABIN7193918

The Mouse Monoclonal anti-SIRPB1 antibody has been validated for ELISA and FACS. It is suitable to detect SIRPB1 in samples from Human.

Quick Overview for SIRPB1 antibody (AA 72-309) (ABIN7193918)

Target: SIRPB1 (Signal-Regulatory Protein beta 1 (SIRPB1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This SIRPB1 antibody is un-conjugated

Application: ELISA, Flow Cytometry (FACS)

Clone: 1A1F4

Product Details anti-SIRPB1 Antibody

Binding Specificity: AA 72-309

Purpose: CD172b Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human CD172b (AA: 72-309) expressed in E. Coli.

Isotype: IgG2b

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for SIRPB1

Target: SIRPB1 (Signal-Regulatory Protein beta 1 (SIRPB1))

Alternative Name: CD172b

Background:

The protein encoded by this gene is a member of the signal-regulatory-protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. This protein was found to interact with TYROBP/DAP12, a protein bearing immunoreceptor tyrosine-based activation motifs. This protein was also reported to participate in the recruitment of tyrosine kinase SYK. Multiple transcript variants encoding different isoforms have been found for this gene.

Molecular Weight: 43.2 kDa

UniProt: O00241